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Article

Allelotyping analysis suggesting a consecutive progression from intratubular germ cell neoplasia to seminoma and then to embryonal carcinoma of the adult testis.

Human pathology - 1 Oct 2013

Miyai Kosuke, Yamamoto Sohei, Iwaya Keiichi, Asano Tomohiko, Tamai Seiichi, Tsuda Hitoshi, Matsubara Osamu

Abstract excerpt

Among adult testicular germ cell tumors, the pathogenesis of embryonal carcinoma remains a matter of debate. Some studies suggest a single consecutive progression from intratubular germ cell neoplasia, unclassified (IGCNU), to seminoma and then to embryonal carcinoma; others suggest that seminoma and embryonal carcinoma derive independently from IGCNU. This allelotyping study aimed to clarify the genetic...

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Identifiers

PMID: 23938161
DOI: 10.1016/j.humpath.2013.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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