Article
High prevalence of p16 genetic alterations in head and neck tumours.
British journal of cancer - 1 Oct 1999
Miracca E C, Kowalski L P, Nagai M A
Abstract excerpt
Inactivation of the p16 gene is believed to contribute to the tumorigenic process of several neoplasms, including head and neck tumours. In the present study, DNA samples from paired tumour and adjacent normal tissue from 47 patients with squamous cell carcinoma of the head and neck were investigated for the occurrence of p16 genetic alterations. Single-strand conformation polymorphism and direct DNA sequence...
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