Article
Alterations of p16INK4a tumour suppressor gene in mucoepidermoid carcinoma of the salivary glands.
International journal of oral and maxillofacial surgery - 1 Apr 2007
Guo X-L, Sun S-Z, Wang W-X, Wei F-C, Yu H-B, Ma B-L
Abstract excerpt
Mucoepidermoid carcinoma (MEC) is common in the salivary glands, but alterations of the p16(INK4a) tumour suppressor gene are largely unknown. The aim of this study was to analyse p16(INK4a) gene alterations in MEC, and evaluate their significance for carcinogenesis. Thirty-eight salivary glands with MEC and six normal salivary glands were studied for p16(INK4a) alterations. In the MEC-affected group, there were...
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