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Article

Alteration in ion channel function of mouse nicotinic acetylcholine receptor by mutations in the M4 transmembrane domain.

The Journal of membrane biology - 15 Jul 1999

Tamamizu S, Lee Y, Hung B, McNamee M G, Lasalde-Dominicci J A

Abstract excerpt

The effect of structural alterations of the M4 transmembrane segment in the Torpedo californica AChR has shown that substitution of specific residues can be critical to the channel gating (Lasalde et al., 1996). In a previous study we found that phenylalanine and tryptophan substitutions at the alphaC418 residue in the M4 transmembrane segment of the Torpedo californica AChR significantly altered ion channel...

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Identifiers

PMID: 10430659
DOI: 10.1007/s002329900545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Alteration in ion channel function of mouse nicotinic acetylcholine receptor by mutations in the M4 transmembrane domain.PMID 10430659Read ↗

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