Location of functional regions of acetylcholine receptor alpha-subunit by site-directed mutagenesis.

doi:10.1038/313364a0

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Article

Location of functional regions of acetylcholine receptor alpha-subunit by site-directed mutagenesis.

Nature - 1 Jan 2000

Mishina M, Tobimatsu T, Imoto K, Tanaka K, Fujita Y, Fukuda K, Kurasaki M, Takahashi H, Morimoto Y, Hirose T

Abstract excerpt

The availability of cloned cDNAs encoding the four subunits of the Torpedo acetylcholine receptor, which can be expressed to make functional receptors in Xenopus oocytes, has made possible a detailed investigation of the functions of the different structural components of the receptor. The functional analysis of receptors with alpha-subunits altered at specific sites by site-directed mutagenesis of the cDNA has...

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PMID: 3838201
DOI: 10.1038/313364a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.