Location of functional regions of acetylcholine receptor alpha-subunit by site-directed mutagenesis.

doi:10.1038/313364a0

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Article

Location of functional regions of acetylcholine receptor alpha-subunit by site-directed mutagenesis.

Nature - 1 Jan 2000

Mishina M, Tobimatsu T, Imoto K, Tanaka K, Fujita Y, Fukuda K, Kurasaki M, Takahashi H, Morimoto Y, Hirose T

Abstract excerpt

The availability of cloned cDNAs encoding the four subunits of the Torpedo acetylcholine receptor, which can be expressed to make functional receptors in Xenopus oocytes, has made possible a detailed investigation of the functions of the different structural components of the receptor. The functi...

Topics

Animals
Base Sequence
Binding Sites
Carbachol
DNA
Gene Expression Regulation
Macromolecular Substances
Membrane Potentials
Mutation
RNA, Messenger
Receptors, Cholinergic
Torpedo
Xenopus

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