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Article

Development of resistance during the early stages of experimental liver carcinogenesis.

Carcinogenesis - 1 Aug 1999

Yusuf A, Rao P M, Rajalakshmi S, Sarma D S

Abstract excerpt

The present study was designed to determine whether the resistant phenotype is acquired at the initiated cell stage itself or requires further exposure to a promoting regimen to express resistance. Male Fischer 344 rats were initiated with diethylnitrosamine (DENA) (200 mg/kg i.p.) and were subjected to either no further treatment or to the resistant hepatocyte (RH) model of liver tumor promotion. Six weeks...

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Source

Identifiers

PMID: 10426821
DOI: 10.1093/carcin/20.8.1641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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