Reduced expression of glutathione S-transferase Yb2 during progression of chemically induced hepatocellular carcinomas in Fischer 344 rats.

doi:10.1016/0270-9139(94)90147-3

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Article

Reduced expression of glutathione S-transferase Yb2 during progression of chemically induced hepatocellular carcinomas in Fischer 344 rats.

Hepatology (Baltimore, Md.) - 1 Jul 1994

Stalker M J, Kocal T E, Quinn B A, Gordon S G, Hayes M A

Abstract excerpt

We followed the expression of several glutathione S-transferase subunits in altered foci, liver neoplasms and metastases produced in male Fischer 344 rats by a modified Solt-Farber protocol, to determine whether components of the resistant phenotype are lost during neoplastic progression. At 6 mo...

Topics

Animals
Cell Transformation, Neoplastic
Chromatography, High Pressure Liquid
Cytosol
Glutathione Transferase
Isoenzymes
Liver
Liver Neoplasms, Experimental
Lung Neoplasms
Male
Phenotype
Rats
Rats, Inbred F344

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Identifiers

PMID: 8020884
DOI: 10.1016/0270-9139(94)90147-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8020884-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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