Article
Quasispecies of hepatitis C virus in serum and in three different parts of the liver of patients with chronic hepatitis.
Hepatology (Baltimore, Md.) - 1 Aug 1999
Sakai A, Kaneko S, Honda M, Matsushita E, Kobayashi K
Abstract excerpt
Hepatitis C virus (HCV) has been known to infect hosts as a quasispecies. Several reports have shown this using serum samples, but there is little information about quasispecies in the liver. In this study, we evaluated quasispecies in serum and in 3 different parts of the liver in 8 patients with varying severity of chronic hepatitis C by calculating nucleotide diversity, entropy, type of substitution and by...
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