Differential sensitivity of hepatitis C virus quasispecies to interferon-alpha therapy.

doi:10.1016/s0168-8278(94)80254-8

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Article

Differential sensitivity of hepatitis C virus quasispecies to interferon-alpha therapy.

Journal of hepatology - 1 Nov 1994

Mizokami M, Lau J Y, Suzuki K, Nakano T, Gojobori T

Abstract excerpt

The quasispecies nature of hepatitis C virus was investigated in a patient with chronic hepatitis C virus infection who underwent interferon-alpha therapy. The hepatitis C virus E2/NS1 region was amplified and cloned, and multiple clones were sequenced before and after interferon-alpha therapy. T...

Topics

Adult
Amino Acid Sequence
Genome, Viral
Genotype
Hepacivirus
Hepatitis C
Humans
Interferon-alpha
Male
Molecular Sequence Data
Mutation
Phylogeny

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