Degree of diversity of hepatitis C virus quasispecies and progression of liver disease.

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Article

Degree of diversity of hepatitis C virus quasispecies and progression of liver disease.

Hepatology (Baltimore, Md.) - 1 Nov 1994

Honda M, Kaneko S, Sakai A, Unoura M, Murakami S, Kobayashi K

Abstract excerpt

We examined the quasispecies of the hepatitis C virus genome in 28 patients with liver disease of varying severity. Nucleotide sequences of the hepatitis C virus genome spanning the region from the core to envelope were used to calculate the nucleotide diversity: 0.58% +/- 0.88% in 5 patients wit...

Topics

Adult
Aged
Base Sequence
Carcinoma, Hepatocellular
Female
Genetic Variation
Genome, Viral
Hepacivirus
Hepatitis C
Hepatitis, Chronic
Humans
Liver Cirrhosis
Liver Neoplasms
Male
Middle Aged
Molecular Sequence Data
Oligonucleotide Probes
Regression Analysis

Source

Open in PubMed

Identifiers

PMID: 7927245

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7927245-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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