Article
Quasispecies dynamics in hepatitis C liver transplant recipients receiving grafts from hepatitis C virus infected donors.
The Journal of general virology - 1 Dec 2015
Pérez-Del-Pulgar Sofía, Gregori Josep, Rodríguez-Frías Francisco, González Patricia, García-Cehic Damir, Ramírez Santseharay, Casillas Rosario, Domingo Esteban, Esteban Juan I, Forns Xavier, Quer Josep
Abstract excerpt
The allocation of liver grafts from hepatitis C virus (HCV)-positive donors in HCV-infected liver transplant (LT) recipients leads to infection with two different viral populations. In a previous study, we examined quasispecies dynamics during reinfection by clonal sequencing, which did not allow an accurate characterization of coexistence and competition events. To overcome this limitation, here we used...
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