Article
Comparison of quasispecies diversity of HCV between chronic hepatitis c and hepatocellular carcinoma by Ultradeep pyrosequencing.
BioMed research international - 1 Jan 2014
Park Chang-Wook, Cho Min-Chul, Hwang Keumrock, Ko Sun-Young, Oh Heung-Bum, Lee Han Chu
Abstract excerpt
BACKGROUNDS: Hepatitis C virus (HCV) exists as population of closely related genetic variants known as quasispecies. HCV quasispecies diversity is strongly influenced by host immune pressure on virus. Quasispecies diversity is expected to decline as host immune response to HCV decreases over natural course of progressing from chronic hepatitis C (CHC) to hepatocellular carcinoma (HCC). METHODS: Ultradeep...
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