Article
p53 gene mutations in non-small cell lung cancer from Thai patients.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Mar 1999
Petmitr S, Makthiengtrong S, Sutinont P, Migasena P
Abstract excerpt
Paraffin embedded tissues from twenty-two Thai patients with non-small cell lung cancer were studied for p53 gene mutations in exon 5 to 8 using polymerase chain reaction and single-stranded conformation polymorphism (PCR-SSCP) followed by thermal cycle sequencing. Results showed that point mutations in this region of p53 gene were present in 3 cases. One harboured the base change from GAC to AAC at codon 281,...
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