Article
TP53 mutations in Korean patients with non-small cell lung cancer.
Journal of Korean medical science - 1 May 2010
Lee Eung Bae, Jin Guang, Lee Shin Yup, Park Ji Young, Kim Min Jung, Choi Jin Eun, Jeon Hyo Sung, Cha Seung Ick, Cho Sukki, Kim Chang Ho, Park Tae-In, Jung Tae Hoon, Son Ji-Woong, Park Jae Yong
Abstract excerpt
Although TP53 mutations have been widely studied in lung cancer, the majority of studies have focused on exons 5-8 of the gene. In addition, TP53 mutations in Korean patients with lung cancers have not been investigated. We searched for mutations in the entire coding exons, including splice sites of the gene, in Korean patients with non-small cell lung cancer (NSCLC). Mutations of the gene were determined by...
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