K-ras oncogene and p53 gene mutations in cholangiocarcinoma from Thai patients.

Article

K-ras oncogene and p53 gene mutations in cholangiocarcinoma from Thai patients.

The Southeast Asian journal of tropical medicine and public health - 1 Mar 1998

Petmitr S, Pinlaor S, Thousungnoen A, Karalak A, Migasena P

Abstract excerpt

Paraffin embedded tissues from twenty Thai patients with intrahepatic cholangiocarcinomas were studied for K-ras gene mutations at codon 12, 13 and 61 and for p53 gene mutations in exon 5 to 8 using polymerase chain reaction and thermal cycle sequencing. Results showed that point mutations at the...

Topics

Adult
Bile Duct Neoplasms
Bile Ducts, Intrahepatic
Cholangiocarcinoma
Female
Genes, p53
Genes, ras
Humans
Male
Middle Aged
Mutation
Polymerase Chain Reaction
Thailand

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