Article
Serum phospholipids are the main environmental determinants of activated factor VII in the most common FVII genotype. European Union Concerted Action "Clotart".
Haematologica - 1 Jul 1999
Mariani G, Bernardi F, Bertina R, Vicente V V, Prydz H, Samama M, Sandset P M, Di Nucci G D, Testa M G, Bendz B, Chiarotti F, Ciarla M V, Strom R
Abstract excerpt
BACKGROUND AND OBJECTIVE: Numerous studies have emphasized the role of triglyceride-rich lipoproteins and of Factor VII (FVII) polymorphisms in determining levels of FVII activity. DESIGN AND METHODS: This study was undertaken to evaluate the role of other lipid fractions and the interaction between lipids and FVII in subjects with recognised genotypes. Volunteer subjects (n=459) from 5 European countries were...
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