Article
Oral contraceptives highlight the genotype-specific association between serum phospholipids and activated factor VII.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 1999
Mariani G, Conard J, Bernardi F, Bertina R, Garcia V V, Prydz H, Samama M, Sandset P M, Puopolo M, Ciarla M V, Poso R, Di Nucci G D, Ceci F, Marchetti G
Abstract excerpt
The present analysis was undertaken to study the effect of oral contraceptive (OC) use on activated factor VII (FVIIa) in subjects characterized by FVII genotypes, with the further aim of evaluating the role of lipids in this pharmacological interaction. In OC users (n=42) and nonusers (n=130) of comparable age, we examined the FVII phenotypic variables (FVII coagulant activity [FVIIc], FVII antigen, and FVIIa),...
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