Article
Plasma factor VII levels are influenced by a polymorphism in the promoter region of the FVII gene.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 1996
Sacchi E, Tagliabue L, Scoglio R, Baroncini C, Coppola R, Bernardi F, Mannucci P M
Abstract excerpt
Genetic factors play a role in determining the variability of plasma factor VII (FVII) levels in healthy individuals. There is also evidence that high serum lipids are associated with high FVII levels in plasma. In the promoter region of the human FVII a DNA polymorphism has been described, originating from a decanucleotide insert present in the less frequent allele. This biallelic system, reflecting the absence...
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