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Activity and levels of factor XIII in a Venezuelan admixed population: association with rs5985 (Val35Leu) and STR F13A01 polymorphisms.

Thrombosis research - 1 Nov 2012

Vívenes Merlyn, Castro de Guerra Dinorah, Rodríguez-Larralde Alvaro, Arocha-Piñango Carmen Luisa, Guerrero Belsy

Abstract excerpt

INTRODUCTION: The single nucleotide polymorphism Val35Leu has been described within the A subunit of gene Factor XIII (FXIII-A) in association with an increase of FXIII activity. In the gene's promoter region STR F13A01 is present, however there is no available data related about its influence on the expression of FXIII. MATERIALS AND METHODS: Blood samples were obtained from apparently healthy and unrelated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22909824
DOI: 10.1016/j.thromres.2012.07.027

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