Article
Influence of factor VII gene polymorphisms and environmental factors on plasma coagulation factor VII concentrations in middle-aged women with and without manifest coronary heart disease.
Thrombosis and haemostasis - 1 Feb 2005
Eriksson-Berg Margita, Deguchi Hiroyuki, Hawe Emma, Scanavini Daniela, Orth-Gomér Kristina, Schenck-Gustafsson Karin, Humphries Steve E, Silveira Angela, Hamsten Anders
Abstract excerpt
Plasma concentrations of coagulation factorVII (FVII) are determined by environmental and genetic factors. The influence of functional polymorphisms in the FVII gene (-670A>C, -402G>A, -401G>T and R353Q) and of established cardiovascular risk factors on plasma concentrations of FVII were investigated in a representative sample of middle-aged women with (n=238) and without (n=220) coronary heart disease (CHD)....
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