Article
T-cell reactivity to GAD65 peptide sequences shared with coxsackie virus protein in recent-onset IDDM, post-onset IDDM patients and control subjects.
Diabetologia - 1 Mar 1997
Schloot N C, Roep B O, Wegmann D R, Yu L, Wang T B, Eisenbarth G S
Abstract excerpt
GAD65 is one of the major autoantigens associated with insulin-dependent diabetes mellitus (IDDM). The two peptides p17 and p18 of GAD65 that share sequence similarity with coxsackie virus (amino acid sequence identity: PEVKEK) appeared to be the major determinants of GAD65 recognized preferably...
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