Article
Analysis of GNAZ gene polymorphism in bipolar affective disorder.
American journal of medical genetics - 20 Aug 1999
Saito T, Papolos D F, Chernak D, Rapaport M H, Kelsoe J R, Lachman H M
Abstract excerpt
Evidence for a bipolar disorder (BPD) susceptibility locus on chromosome 22q11 has been provided in several studies. One candidate gene that maps to this region is the G-protein alpha subunit gene Galphaz (GNAZ). We have identified a common silent polymorphism in GNAZ exon 2 by single strand conformation polymorphism analysis. The frequency of this polymorphism was determined in a control population (n=84) and in...
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