Article
Association between anxiety and non-coding genetic variants of the galanin neuropeptide.
PloS one - 1 Jan 2019
Keszler Gergely, Molnár Zsuzsanna, Rónai Zsolt, Sasvári-Székely Mária, Székely Anna, Kótyuk Eszter
Abstract excerpt
BACKGROUND: Galanin, an inhibitory neuropeptide and cotransmitter has long been known to co-localize with noradrenaline and serotonin in the central nervous system. Several human studies demonstrated altered galanin expression levels in major depressive disorder and anxiety. Pharmacological modulation of galanin signaling and transgenic strategies provide further proof for the involvement of the galanin system in...
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