Article
Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder.
Journal of affective disorders - 1 Jan 2008
Unschuld Paul G, Ising Marcus, Erhardt Angelika, Lucae Susanne, Kohli Martin, Kloiber Stefan, Salyakina Daria, Thoeringer Christoph K, Kern Nikola, Lieb Roselind, Uhr Manfred, Binder Elisabeth B, Müller-Myhsok Bertram, Holsboer Florian, Keck Martin E
Abstract excerpt
BACKGROUND: Galanin (GAL) is a neuropeptide, which is expressed primarily in limbic nuclei in the brain and mediates miscellaneous physiological processes and behaviors. In animal studies, both the application of GAL and antagonism of its receptors have been shown to affect anxiety-like and depression-related behavior. In humans, intravenous administration of the neuropeptide galanin has been reported to have...
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