Differential distribution of somatostatin sst2 receptor splice variants in rat gastric mucosa.

doi:10.1007/s004410051344

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Article

Differential distribution of somatostatin sst2 receptor splice variants in rat gastric mucosa.

Cell and tissue research - 1 Jul 1999

Schindler M, Humphrey P P

Abstract excerpt

The tetradecapeptide somatostatin (SRIF) has an inhibitory action on acid secretion in the stomach. It has been suggested that somatostatin may act directly on parietal cells as well as indirectly via histamine-producing cells. A family of high affinity membrane-bound receptors, which are termed sst1-sst5 receptors, mediates the physiological effects of somatostatin. On the basis of functional studies it has been...

Topics

Alternative Splicing
Amino Acid Sequence
Animals
Epitopes
Female
Gastric Mucosa
Genetic Variation
Immunohistochemistry
Molecular Sequence Data
Peptide Fragments
Rats
Rats, Sprague-Dawley
Receptors, Somatostatin

Source

Open in PubMed

Identifiers

PMID: 10398894
DOI: 10.1007/s004410051344

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