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Article

Yeast Dam1p has a role at the kinetochore in assembly of the mitotic spindle.

Proceedings of the National Academy of Sciences of the United States of America - 20 Nov 2001

Jones M H, He X, Giddings T H, Winey M

Abstract excerpt

During mitosis, replicated chromosomes are separated to daughter cells by the microtubule-based mitotic spindle. Chromosomes attach to the mitotic spindle through specialized DNA/protein structures called kinetochores, but the mechanism of attachment is not well understood. We show here that the yeast microtubule-binding protein, Dam1p, associates physically and functionally with kinetochores, suggesting a role...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11698664
DOI: 10.1073/pnas.241417098
PMCID: PMC61100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Yeast Dam1p has a role at the kinetochore in assembly of the mitotic spindle.PMID 11698664Read ↗

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The phosphorylation of a kinetochore protein Dam1 by Aurora B/Ipl1 kinase promotes chromosome bipolar attachment in yeast.Semantic proximity Read ↗

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Dad1p, third component of the Duo1p/Dam1p complex involved in kinetochore function and mitotic spindle integrity.Semantic proximity Read ↗

Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle function.Semantic proximity Read ↗

Laterally attached kinetochores recruit the checkpoint protein Bub1, but satisfy the spindle checkpoint.Semantic proximity Read ↗

A mitotic role for Mad1 beyond the spindle checkpoint.Semantic proximity Read ↗

Drosophila CENP-A mutations cause a BubR1-dependent early mitotic delay without normal localization of kinetochore components.Semantic proximity Read ↗

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The C-terminal half of Saccharomyces cerevisiae Mad1p mediates spindle checkpoint function, chromosome transmission fidelity and CEN association.Semantic proximity Read ↗

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