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Article

A pathway containing the Ipl1/aurora protein kinase and the spindle midzone protein Ase1 regulates yeast spindle assembly.

Developmental cell - 1 Sept 2007

Kotwaliwale Chitra V, Frei Stéphanie Buvelot, Stern Bodo M, Biggins Sue

Abstract excerpt

It is critical to elucidate the pathways that mediate spindle assembly and therefore ensure accurate chromosome segregation during cell division. Our studies of a unique allele of the budding yeast Ipl1/Aurora protein kinase revealed that it is required for centrosome-mediated spindle assembly in the absence of the BimC motor protein Cin8. In addition, we found that the Ase1 spindle midzone-associated protein is...

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Identifiers

PMID: 17765685
DOI: 10.1016/j.devcel.2007.07.003
PMCID: PMC2679386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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