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Article

UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles.

Molecular biology of the cell - 1 Jul 1999

Nonet M L, Holgado A M, Brewer F, Serpe C J, Norbeck B A, Holleran J, Wei L, Hartwieg E, Jorgensen E M, Alfonso A

Abstract excerpt

The unc-11 gene of Caenorhabditis elegans encodes multiple isoforms of a protein homologous to the mammalian brain-specific clathrin-adaptor protein AP180. The UNC-11 protein is expressed at high levels in the nervous system and at lower levels in other tissues. In neurons, UNC-11 is enriched at presynaptic terminals but is also present in cell bodies. unc-11 mutants are defective in two aspects of synaptic...

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Identifiers

PMID: 10397769
DOI: 10.1091/mbc.10.7.2343
PMCID: PMC25452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles.PMID 10397769Read ↗

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