Article
Inherited susceptibility to bleomycin-induced chromatid breaks in cultured peripheral blood lymphocytes.
Journal of the National Cancer Institute - 7 Jul 1999
Cloos J, Nieuwenhuis E J, Boomsma D I, Kuik D J, van der Sterre M L, Arwert F, Snow G B, Braakhuis B J
Abstract excerpt
BACKGROUND: Susceptibility to bleomycin-induced chromatid breaks in cultured peripheral blood lymphocytes may reflect the way a person deals with carcinogenic challenges. This susceptibility (also referred to as mutagen sensitivity) has been found to be increased in patients with environmentally related cancers, including cancers of the head and neck, lung, and colon, and, in combination with carcinogenic...
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