Article
Microarray analysis of bleomycin-exposed lymphoblastoid cells for identifying cancer susceptibility genes.
Molecular cancer research : MCR - 1 Feb 2006
Cloos Jacqueline, de Boer Wim P H, Snel Mireille H J, van den Ijssel Paul, Ylstra Bauke, Leemans C René, Brakenhoff Ruud H, Braakhuis Boudewijn J M
Abstract excerpt
The uncovering of genes involved in susceptibility to the sporadic cancer types is a great challenge. It is well established that the way in which an individual deals with DNA damage is related to the chance to develop cancer. Mutagen sensitivity is a phenotype that reflects an individual's susceptibility to the major sporadic cancer types, including colon, lung, and head and neck cancer. A standard test for...
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