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Bleomycin-induced chromosome breaks as a risk marker for lung cancer: a case-control study with population and hospital controls

1 Feb 2003

Abstract excerpt

Environmental exposure to carcinogens and individual susceptibility play significant roles in cancer risk. Suboptimal DNA repair capability, measured by quantifying mutagen-induced chromosome breaks, might explain variable host susceptibility to environmental carcinogens. In an ongoing lung cancer case-control study, we compared individual sensitivity to bleomycin-induced chromosome breaks in 152 non-small cell...

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PMID: 12584177
DOI: 10.1093/carcin/24.2.269

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