Article
Radiation-induced chromatid breaks as a predictor of breast cancer risk.
International journal of radiation oncology, biology, physics - 1 Feb 2001
Buchholz T A, Wu X
Abstract excerpt
PURPOSE: In in vivo models, radiation-induced genomic instability correlates with the risk of breast cancer development. In addition, homozygous mutations in tumor suppressor genes associated with breast cancer development adversely affects the processing and repair of radiation-induced DNA damage. We performed a case-control study to determine whether an assay measuring radiation-induced chromatid breaks...
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