Article
Mutagen sensitivity in patients with familial and non-familial urothelial cell carcinoma.
International journal of cancer - 1 Nov 2000
Aben K K, Cloos J, Koper N P, Braakhuis B J, Witjes J A, Kiemeney L A
Abstract excerpt
Due to variation in individual susceptibility, only a fraction of all individuals exposed to environmental carcinogens will develop cancer. Our aim was to assess whether mutagen sensitivity plays a role in developing urothelial cell carcinoma (UCC) and whether this sensitivity is different in familial and non-familial cases. Intrinsic susceptibility was quantified by a mutagen sensitivity assay (mean number of...
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