Article
Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes.
British journal of pharmacology - 1 May 1999
Ueno S, Wick M J, Ye Q, Harrison N L, Harris R A
Abstract excerpt
1. Mutations of specific amino acids were introduced in transmembrane domains (TM) of GABA(A) receptor alpha2, beta1 and gamma2L subunits. The effects of these mutations on the action of ethanol were studied using the Xenopus oocyte expression system and two-electrode voltage-clamp recording tech...
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