Article
IL1B gene polymorphisms influence the course and severity of inflammatory bowel disease.
Immunogenetics - 1 Jun 1999
Nemetz A, Nosti-Escanilla M P, Molnár T, Köpe A, Kovács A, Fehér J, Tulassay Z, Nagy F, García-González M A, Peña A S
Abstract excerpt
There is evidence of a disbalance in the inflammatory regulation of patients with inflammatory bowel diseases (IBD). Interleukin-1 beta plays an important role in the pro-inflammatory response. Our aim was to study the influence which IL1B gene polymorphisms may have on the severity and course of these diseases. Ninety-six patients with ulcerative colitis (UC), 98 patients with Crohn's disease (CD), and 132...
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