Article
Association of beta-defensin 1 single nucleotide polymorphisms with Crohn's disease.
Scandinavian journal of gastroenterology - 1 Mar 2008
Kocsis Agnes Katalin, Lakatos Peter Laszló, Somogyvári Ferenc, Fuszek Peter, Papp János, Fischer Simon, Szamosi Tamás, Lakatos Laszlo, Kovacs Agota, Hofner Peter, Mándi Yvette
Abstract excerpt
OBJECTIVE: It has been suggested that deficient defensin expression is associated with the chronic inflammation of Crohn's disease. The regional localization of Crohn's disease, ileal or colonic disease can be linked to different defensin profiles. As constitutive beta-defensin 1 has a colonic expression, we considered it of interest to investigate single nucleotide polymorphisms (SNPs) of the beta-defensin 1...
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