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Article

Polymorphisms of the IL-1beta and IL-1beta-inducible genes in ulcerative colitis.

Journal of gastroenterology - 1 Nov 2002

Nohara Hiroaki, Saito Yuki, Higaki Singo, Okayama Naoko, Hamanaka Yuichiro, Okita Kiwamu, Hinoda Yuji

Abstract excerpt

BACKGROUND: Ulcerative colitis (UC) is a chronic disorder of undetermined etiology, but a genetic predisposition to UC is well recognized. Among cytokines induced in UC, interleukin 1 (IL-1) appears to have a central role because of its immunological upregulatory and proinflammatory activities. The aim of this study was to assess whether UC is associated with polymorphisms of the IL-1beta gene and three...

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Identifiers

PMID: 12572877
DOI: 10.1007/BF03326427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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