Article
Association of interleukin 1 gene family polymorphisms with duodenal ulcer disease.
Clinical and experimental immunology - 1 Dec 2003
García-González M A, Lanas A, Savelkoul P H M, Santolaria S, Benito R, Crusius J B A, Peña A S
Abstract excerpt
Cytokine genes taking part in the immunological response to Helicobacter pylori infection are good candidates to study for genetic predisposition to duodenal ulcer disease (DU). Among cytokines, interleukin (IL)-1beta and its natural specific inhibitor, the interleukin-1 receptor antagonist, are cytokines that play a key role in regulating gastric acid secretion and modulating the immune response in the...
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