Article
Detection of p53 gene mutations in human leukemia by PCR-SSCP analysis and direct nucleotide sequencing.
Chinese medical journal - 1 Apr 1998
Wang R, Yu Z, Gu J, Li D, Wang M, Cao Y
Abstract excerpt
OBJECTIVE: To look for mutations of the p53 gene in leukemic patients and study the relationship between abnormalities in p53 gene and leukemogenesis. METHODS: The peripheral blood and Bone Marrow Samples were collected from 36 patients with various leukemia types including 14 cases of lymphocytic leukemia [8 cases of acute lymphocytic leukemia (ALL), 4 cases of chronic lymphocytic leukemia (CLL), 2 cases of...
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