Adult T-cell leukemia: structures and expression of the p53 gene.

doi:10.1002/ijc.2910490614

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Article

Adult T-cell leukemia: structures and expression of the p53 gene.

International journal of cancer - 2 Dec 1991

Sugito S, Yamato K, Sameshima Y, Yokota J, Yano S, Miyoshi I

Abstract excerpt

Experiments were undertaken to investigate a genetic event involved in leukemogenesis in adult T-cell leukemia (ATL). For this purpose, the p53 gene was chosen for study, since alteration of the gene has been found in a wide variety of human cancers. Structures and expression of the p53 gene in ATL cells were investigated by Southern and Northern blot analyses and a polymerase-chain-reaction single-strand...

Topics

Adult
Aged
Base Sequence
Blotting, Northern
Blotting, Southern
Codon
DNA, Neoplasm
Female
Gene Expression
Genes, p53
Humans
Leukemia, T-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Molecular Sequence Data

Mutation

Oligodeoxyribonucleotides

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 1959992
DOI: 10.1002/ijc.2910490614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1959992-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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