Article
Adult T-cell leukemia: structures and expression of the p53 gene.
International journal of cancer - 2 Dec 1991
Sugito S, Yamato K, Sameshima Y, Yokota J, Yano S, Miyoshi I
Abstract excerpt
Experiments were undertaken to investigate a genetic event involved in leukemogenesis in adult T-cell leukemia (ATL). For this purpose, the p53 gene was chosen for study, since alteration of the gene has been found in a wide variety of human cancers. Structures and expression of the p53 gene in ATL cells were investigated by Southern and Northern blot analyses and a polymerase-chain-reaction single-strand...
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