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Article

Srp2, an SR protein family member of fission yeast: in vivo characterization of its modular domains.

Nucleic acids research - 1 Jul 1999

Lützelberger M, Gross T, Käufer N F

Abstract excerpt

We isolated srp2, a gene encoding a protein composed of two RNA binding domains (RBDs) at the N-terminus followed by an arginine-rich region that is flanked by two short SR (serine/arginine) elements. The RBDs contain the signatures RDADDA and SWQDLKD found in RBD1 and RBD2 of all typical metazoan SR proteins. srp2 is essential for growth. We have analyzed in vivo the role of the modular domains of Srp2 by...

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Identifiers

PMID: 10373577
DOI: 10.1093/nar/27.13.2618
PMCID: PMC148469

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