Article
Isolation of synthetic lethal mutations in the rsm1-null mutant of fission yeast.
Journal of microbiology (Seoul, Korea) - 1 Oct 2010
Moon DongGeRaMi, Park Yun-Sun, Kim Cha-Yeon, Yoon Jin Ho
Abstract excerpt
To identify mutations in genes that are genetically linked to rsm1, we performed a synthetic lethal genetic screen in the fission yeast, Schizosaccharomyces pombe. Four mutations that showed synthetic lethality in combination with the rsm1null allele were isolated from approximately 320,000 colonies and defined in three complementation groups. One mutant (SLrsm1) exhibited a significant accumulation of poly(A)(+)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
