Article
Yeast Srp1p has homology to armadillo/plakoglobin/beta-catenin and participates in apparently multiple nuclear functions including the maintenance of the nucleolar structure.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jul 1994
Yano R, Oakes M L, Tabb M M, Nomura M
Abstract excerpt
SRP1, a suppressor of certain temperature-sensitive mutations in RNA polymerase I in Saccharomyces cerevisiae, encodes a protein that is associated with nuclear pores. By using a system of conditional SRP1 expression and by isolating temperature-sensitive srp1 mutants, we have demonstrated that S...
Topics
- Amino Acid Sequence
- Animals
- Armadillo Domain Proteins
- Cell Nucleolus
- Cell Nucleus
- Cytoskeletal Proteins
- Desmoplakins
- Drosophila Proteins
- Microtubules
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Proteins
- RNA Polymerase I
- Repetitive Sequences, Nucleic Acid