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Article

Is the LDL receptor-related protein involved in Alzheimer's disease?

Neurogenetics - 1 Apr 1999

Lambert J C, Chartier-Harlin M C, Cottel D, Richard F, Neuman E, Guez D, Legrain S, Berr C, Amouyel P, Helbecque N

Abstract excerpt

LDL-related protein receptor (LRP) is the main receptor in the brain for apolipoprotein E. Moreover, the LRP gene is located on chromosome 12, the site of a potential Alzheimer's disease (AD) locus. We explored the association between the LRP gene and AD in 600 French Caucasian patients (37.8% men, mean age 72.0+/-8.0 years, mean age at onset 68.7+/-8.1 years) and age-matched controls (n=646, 37.0% men, mean age...

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Identifiers

PMID: 10369887
DOI: 10.1007/s100480050061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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