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Article

Mutation detection by stacking hybridization on genosensor arrays.

Molecular biotechnology - 1 Feb 1999

Maldonado-Rodriguez R, Espinosa-Lara M, Loyola-Abitia P, Beattie W G, Beattie K L

Abstract excerpt

A new strategy for analysis of point mutations using oligonucleotide array (genosensor) hybridization was investigated. In the new approach, a single-stranded target strand is preannealed with a labeled "stacking oligonucleotide," and then the partially duplex labeled target molecule is hybridized to an array of glass-tethered oligonucleotide probes, targeted to the region on the target immediately adjacent to...

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PMID: 10367279
DOI: 10.1007/BF02789173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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