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Article

Astrogliosis and the ApoE genotype. an immunohistochemical study of postmortem human brain tissue.

Dementia and geriatric cognitive disorders - 1 Jan 2000

Overmyer M, Helisalmi S, Soininen H, Laakso M, Riekkinen P, Alafuzoff I

Abstract excerpt

Significantly increased glial fibrillary acidic protein (GFAP) expression was seen in postmortem brain tissue from demented patients with Alzheimer's disease (AD) (73 cases, 61 females/12 males, mean age 84 +/- 9 years) compared to controls (22 cases, 10 females/12 males, mean age 78 +/- 9 years). In demented patients, the GFAP expression, counts of AD lesions, senile/neuritic plaques (SP/NP) and neurofibrillary...

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Share to Apolipoprotein E4
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10364641
DOI: 10.1159/000017128

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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