Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E genotype, Alzheimer's pathologies and related gene expression in the aged population.

Brain research. Molecular brain research - 1 Mar 1995

Oyama F, Shimada H, Oyama R, Ihara Y

Abstract excerpt

We have investigated the effect of genotypes of apolipoprotein E (ApoE) on the pathologies found in Alzheimer's disease (AD) and its related gene expression in 38 aged human brains obtained from consecutive autopsied cases. ApoE2/3, -3/3, -3/4, and -4/4 were typed in those aged brains, with ApoE3/3 being most prevalent. The AD pathologies were undetectable in ApoE2/3 brains, but were frequently observed in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Gene Expression

Share to Genotype

Share to Molecular Sequence Data

Share to RNA, Messenger

Source

Identifiers

PMID: 7770005
DOI: 10.1016/0169-328x(94)00233-5

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E genotype, Alzheimer's pathologies and related gene expression in the aged population.PMID 7770005Read ↗

Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype.Semantic proximity Read ↗

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.Semantic proximity Read ↗

Apolipoprotein E polymorphism and susceptibility to Alzheimer's disease.Semantic proximity Read ↗

Genotype-related differences of hippocampal apolipoprotein E levels only in early stages of neuropathological changes in Alzheimer's disease.Semantic proximity Read ↗

Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease.Semantic proximity Read ↗

The spectrum of preclinical Alzheimer's disease pathology and its modulation by ApoE genotype.Semantic proximity Read ↗

Apolipoprotein E (APOE) polymorphism influences serum APOE levels in Alzheimer's disease patients and centenarians.Semantic proximity Read ↗

Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent.Semantic proximity Read ↗

Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types. Significance for etiological theories of Alzheimer's disease.Semantic proximity Read ↗

Inconstant apolipoprotein E (ApoE)-like immunoreactivity in amyloid beta protein deposits: relationship with APOE genotype in aging brain and Alzheimer's disease.Semantic proximity Read ↗

Influence of apolipoprotein E genotype on cerebral amyloid angiopathy in the elderly.Semantic proximity Read ↗

Apolipoprotein E as vascular risk factor in neurodegenerative dementia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.