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Article

Population variation in glial fibrillary acidic protein levels in brain ageing: relationship to Alzheimer-type pathology and dementia.

Dementia and geriatric cognitive disorders - 1 Jan 2009

Wharton S B, O'Callaghan J P, Savva G M, Nicoll J A R, Matthews F, Simpson J E, Forster G, Shaw P J, Brayne C, Ince P G

Abstract excerpt

BACKGROUND: The cellular pathology of astrocytes in brain ageing and their role in modulating the brain's response to neurodegenerative pathology remain incompletely understood. METHODS: Using quantitative ELISA, we have investigated glial fibrillary acidic protein (GFAP) expression in the population-based neuropathology cohort of the Medical Research Council Cognitive Function and Ageing Study to determine: (1)...

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Source

Identifiers

PMID: 19420941
DOI: 10.1159/000217729

Genes

GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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