Article
A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression.
Biochemical and biophysical research communications - 7 Jun 1999
Rovin B H, Lu L, Saxena R
Abstract excerpt
Two novel polymorphisms in the distal regulatory region of the MCP-1 gene were identified by directly sequencing PCR amplified genomic DNA. These polymorphisms are located at positions -2518 (G or A) and -2076 (A or T) relative to the major transcriptional start site of the gene. To examine the effect of these polymorphisms on MCP-1 transcription, polymorphic variants of the MCP-1 distal regulatory region were...
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