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Article

Genetic variation in the Mcp-1 gene promoter associated with the risk of polycystic ovary syndrome.

PloS one - 1 Jan 2015

Li Lan, Ryoo Ji Eun, Lee Kyung-Ju, Choi Bum-Chae, Baek Kwang-Hyun

Abstract excerpt

Monocyte chemoattractant protein-1 (MCP-1) is a pivotal chemokine in the inflammatory response, which plays an important role in recruiting monocytes to sites of injury and infection. However, the exact mechanism of Mcp-1 associated with PCOS risk was unknown. In this study, we explored whether the Mcp-1 -2518G>A polymorphism increases the risk of PCOS. We performed a comparative study of -2518G>A polymorphism of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 25902044
DOI: 10.1371/journal.pone.0123045
PMCID: PMC4406762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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